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NCOA4-mediated FTH1 degradation is one explanation for the intracellular ferrous iron accumulation after ph-IOP, because knockdown of Ncoa4 inhibited FTH1 degradation, thereby alleviating ferrous iron accumulation

2020 [cited 2024 Aug 2];12:2867

19 (14):2088-103 Available from: 17

Unlike normal cells, which rely on oxidative phosphorylation, most cancers exhibit the Warburg effect, favoring aerobic glycolysis despite its low ATP yield (2 mol ATP/mol glucose) [35]