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Therefore, persistent interactions with misfolded or metastable proteins can overload the chaperone system, thereby ultimately compromising global protein homeostasis

The culture plates were precoated with 2 g/ml -1 anti-mouse CD3 and 2 g/ml -1 anti-mouse CD28 antibodies overnight at 4 C

[DOI] [PMC free article] [PubMed] [Google Scholar] [83].Bosch X, Ramos-Casals M, Khamashta MA

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