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Psychiatry 42 , 349358 (1997)

Selby et al

B12 is especially beneficial for individuals who have difficulty absorbing B12 from food or oral supplements, which can occur due to certain digestive disorders, age-related changes, or specific medical conditions

In human ALS motor cortex, microglia show increased expression of Iba1 and CD68 (i.e., macrophages and monocytes marker), with CD68 levels strongly correlating with TDP-43 pathology (Swanson et al., 2023)