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(Access-Medicine) rxlist.com (Desferal ) Keywords Folic acid Trade Name: Folvite Drug Class: Drug used in anemia (megaloblastic) Mechanism of Action: Essential cofactor for synthesis of amino acids, purines and DNA Indications: Treatment of megaloblastic anemias due to a deficiency of folic acid as may be seen in tropical or non-tropical sprue, in anemias of nutritional origin, pregnancy, infancy, or childhood A reduced form of folic acid known as citrovorum factor (or leucovorin) is given to replenish endogenous folic acid in patients on methotrexate (which inhibits dihydrofolate reductase)