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As previously mentioned, iron accumulation, glutathione (GSH) depletion, GPx4 inactivation, and lipid peroxidation (LPO) are key features of ferroptosis, and these characteristics are also observed in the intestinal epithelial cells of IBD patients and mice

Integrating the available body of evidence suggests that depression, understood as a complex disorder, may derive significant advantages from therapeutic interventions that can concurrently rectify neurotransmitter dysregulation, enhance neuroplastic function, and mitigate chronic inflammatory processes

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Shimizu, I., & Minamino, T