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Olivier Niggli, WADAs Director General, said: We encourage athletes, their entourage and all stakeholders to acquaint themselves with the Summary of Major Modifications to avoid inadvertent use of substances and methods that are prohibited in sport for 2025. Athletes and their support personnel should make themselves aware of the changes, review any medications they use, and apply for a TUE, if required, before the updated list comes into effect on 1 January 2025

A novel class of therapeutics is represented by the anti-miR oligonucleotides (Figure 2)