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July 20, 2025

We observed that common adverse events such as nasopharyngitis, diarrhoea and headache, which have been documented in previous trials and various retrospective case analyses, did not show a positive signal in disproportionality analysis ( Significant signals are observed with Exposure during pregnancy

Rats treated with CS and Fe 3 O 4 NPs showed no significant changes in serum urea, creatinine, and uric acid levels compared to rats with ARF (F 2,15 = 0.2608, F 2,15 = 4.058, F 2,15 = 3.578, respectively)

Nevertheless, it is important to note that there is a lack of studies examining the priority and specificity of these enzymes in regulating lactylation, which complicates the determination of the optimal conditions for catalyzing this modification