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Epigenetic factors regulation in normal colon The gut epithelium continues to be the ideal model for investigating the processes of normal and pathological differentiation processes

Under various stress conditions, such as amino acid starvation, endoplasmic reticulum stress, hypoxia and virus infection, ATF4 (a member of the ATF/CREB transcription factor family) is mainly induced by mRNA translation (Pakos-Zebrucka et al., 2016)

Finally, the oxidative stress and protein nitration causes the opening of the mitochondrial membrane transition pore (MPTP) leading to the collapse of the membrane potential and cessation of ATP synthesis, which is the cause of cell death [37, 38]

The effect of physical activity on sleep quality and sleep disorder: a systematic review