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Previous studies in patients with diabetes demonstrated that intravenous l-carnitine administration could improve insulin sensitivity [12, 13]

Furthermore, the included studies were heterogeneous concerning the characteristics of patients and study design (2 of studies on L-carnitine supplementation have been performed in the setting of hemodialysis when carnitine metabolism is altered in uremia and the depletion of carnitine is expected 62 , 4 in diabetic/metabolic syndrome patients with dyslipidemia and 1 in hyperlipidemic patients)

Secondary coenzyme Q 10 deficiency has also been identified in non-mitochondrial disorders, such as cardiofaciocutaneous syndrome and Niemann-Pick-type C disease (11)

L-karnityna to aminokwas niezbdny do transportu kwasw tuszczowych do mitochondriw , gdzie s one wykorzystywane do produkcji energii