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The carboxyl-terminal fragment of hGH corresponding to amino acids 177191 (AOD9604) was shown to act as a lipid mobilizing domain with inhibitory action on acetyl-CoA carboxylase (ACC) activity in hepatocytes and adipocytes

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In addition, exacerbation of the reduction in ATP and observed phosphocreatine levels, is accompanied by an increase in ADP and orthophosphate levels, in both cardiac tissue and other organs (30)