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Erastin and RSL3 are specific inducers of ferroptosis by inhibiting System X c and GPX4, respectively

Brown found that the separation of breast cancer cells from the extracellular matrix (ECM) significantly decreased cell viability, whereas cell viability was improved by the ferroptosis inhibitor Fer-1, demonstrating that separation of cells from the ECM is a pro-ferroptosis response

Inhibitors Rhein - a major metabolite of sennoside A and B