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Some studies have shown that metformin can reduce the absorption of vitamin B12 in 30% of people with type 2 diabetes (Vitamin B12 deficiency in metformin-treated type-2 diabetes patients, prevalence and association with peripheral neuropathy)

The role of astrocyte-mediated plasticity in neural circuit development and function

The practice is based on the belief that higher levels of Vitamin C can yield increased health benefits, particularly in terms of immune system support

A longer study period is also recommended to confirm whether these benefits are sustained and clinically relevant in disease prevention [38]