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In several meta-analyses, UPT was found to be the most effective small molecule drug for inducing clinical remission and clinical response, but it had the highest incidence of adverse events in patients with moderate to severe UC [12, 179]

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Recombinant Human Arginase I (rhArgI) for Patients with Advanced Hepatocellular Carcinoma (HCC): an Adaptive Design Dose Escalation Trial with Addition of Standard Doxorubicin Treatment