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doi: 10.1007/s00280-009-1041-6 18 KaravasilisVKotoulaVPentheroudakisGTelevantouDLambakiSChrisafiSet al

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PI3K/Akt-Nrf2 interactions When growth factors are activated in normal cells, PI3K signaling, and downstream Akt and mTOR induce enhanced glycolytic flux and fatty acid synthesis [62]