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Addressing these translational gaps and prioritizing both mechanistic depth and clinical validation will be critical to translating preclinical discoveries into actionable therapies for heat stress-induced liver injury

Long-term management typically involves gradually increasing dietary fiber once the flare resolves, to help prevent future episodes

For instance, a study in 2024 showed that when the concentration of bilirubin in serum reaches a certain value, the antioxidant effect of bilirubin begins to reduce, and even induces oxidative stress and thus promotes the development of cancer (183)

In de biochemie betekent 'gereduceerd' dat een stof elektronen heeft opgenomen en daardoor in staat is om andere moleculen te beschermen tegen oxidatie