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Future Perspectives and Challenges Ferroptosis was initially discovered as a novel form of RCD in 2012, and its underlying transduction mechanisms have recently gained increasing attention in cancer research ( , GPX4, FSP1 and BH1), various ferroptosis inducers and techniques have been discovered and potentially applied in cancer treatment (Figure 7)

Mitochondrial respiration was impaired in all CAP-containing conditions where MT-CO2 protein levels were decreased as a consequence of loss of mitochondrial protein synthesis (Fig

66 YuQ.LiuY.CaoC.LeF.QinX.SunD.et al (2014)

252,253 The LPAR6 antagonists C75 and XAA suppressed HCC progression