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doi: 10.1016/j.tem.2008.07.005

J Clin Oncol 24 (Suppl 18) Miller KD et al

These risks are theoretical, not documented in human trials, but they are reasons community references include cycle off-periods

Similarly, zlem Krolu et al., 2019 [60] also utilized 5% dextrose and provided a detailed mechanism, suggesting that dextrose induces mild osmotic stress, triggering a localized proliferative response, potentially via fibroblast stimulation and angiogenic gene expression [60]