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After stopping a CYP3A4 inducer, as the effects of the inducer decline, the hydrocodone plasma concentration will increase (see CLINICAL PHARMACOLOGY), which could increase or prolong both the therapeutic effects and adverse reactions, and may cause serious respiratory depression

Based on the previous layout, we postulated that SP and L-car might mutually enhance their antioxidant capacities, ultimately providing a more prolonged protective effect than either could supply on its own

While generally well-tolerated, some individuals may experience digestive upset, headaches, or fatigue, with rarer reactions requiring professional medical guidance